ARIC: The Atherosclerosis Risk in Communities Study (ARIC), sponsored by the National Heart, Lung, and Blood Institute (NHLBI) is a prospective epidemiologic study conducted in four U.S. communities. ARIC is designed to investigate the causes of atherosclerosis and its clinical outcomes, and variation in cardiovascular risk factors, medical care, and disease by race, gender, location, and date. To date, the ARIC study has published over 2,000 articles in peer-reviewed journals. The PAGE ARIC PI is Dr. Kari North.
BioMe: BioMe is an electronic medical record-linked biobank at the Icahn School of Medicine at Mount Sinai that enables researchers to rapidly and efficiently conduct genetic, epidemiologic, molecular, and genomic studies on large collections of research specimens linked with medical information. It is funded by The Charles Bronfman Institute for Personalized Medicine. The PAGE BioMe PI is Dr. Ruth Loos.
CARDIA: The Coronary Artery Risk Development in Young Adults (CARDIA) study aims to identify factors that begin in young adulthood, which is two to three decades before the onset of cardiovascular disease in later life. The CARDIA study is designed to examine the factors that contribute to the development of cardiovascular disease, as well as to better understand the natural history of cardiovascular disease over the entire adult life. The PAGE CARDIA PI is Dr. Myriam Fornage.
HCHS/SOL: The Hispanic Community Health Study / Study of Latinos (HCHS/SOL) is a multi-center epidemiologic study in Hispanic/Latino populations to assess the role of acculturation in the prevalence and development of disease, and to identify factors playing a protective or harmful role in the health of Hispanics/Latinos. The target population of 16,000 persons of Hispanic/Latino origin, specifically Cuban, Puerto Rican, Dominican, Mexican, and Central/South American, were recruited through four Field Centers in Miami, San Diego, Chicago and the Bronx area of New York. The PAGE HCHS/SOL PI is Dr. Kari North.
MEC The Multiethnic Cohort Study (MEC) is a large epidemiological study which follows over 215,000 residents of Hawaiʻi and Los Angeles for development of cancer and other chronic diseases. It includes men and women of five main ethnic groups: Japanese Americans, Native Hawaiians, African Americans, Latinos, and whites. The PAGE MEC PIs are Dr. Chris Haiman and Dr. Loic Lemarchand.
MESA: The Multi-Ethnic Study of Atherosclerosis (MESA) is a study of the characteristics of subclinical cardiovascular disease (disease detected non-invasively before it has produced clinical signs and symptoms) and the risk factors that predict progression to clinically overt cardiovascular disease or progression of the subclinical disease. MESA researchers study a diverse, population-based sample of 6,814 asymptomatic men and women aged 45-84. Approximately 38 percent of the recruited participants are white, 28 percent African-American, 22 percent Hispanic, and 12 percent Asian, predominantly of Chinese descent. The PAGE MESA PI is Dr. Steven Rich.
WHI: The Women’s Health Initiative (WHI) is a long-term national health study funded by the National Heart, Lung, and Blood Institute, or NHLBI. The original WHI study began in the early 1990s and concluded in 2005. Since 2005, the WHI has continued as Extension Studies, which are annual collections of health updates and outcomes in active participants. The second Extension Study enrolled 93,500 women in 2010 and follow-up of these women continues. As with the original WHI study, the main areas of research are cardiovascular disease, cancers, and osteoporotic fractures. While WHI continues to focus on strategies to prevent the major causes of death, disability, and frailty in older women, the breadth and richness of the WHI data allow for the exploration and investigation of many more research questions on women’s health and aging. The PAGE WHI PI is Dr. Charles Kooperberg.